Sunday, March 15, 2015
Chronic Hepatitis
Inflammation is initially limited to portal tracts and consists of lymphocytes, macrophages, occasional plasma cells; forming Lymphoid aggregates
periportal necrosis and bridging necrosis
Portal and periportal fibrosis
Formation of bridging fibrous septa
HBV: "ground-glass" hepatocytes, "sanded" nuclei
HCV: bile duct epithelial cell proliferation, lymphoid aggregate formation
Cirrhosis: The end-stage outcome
Fibrosis with regenerative nodules with proliferating hepatocytes.
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