Showing posts with label penicillin. Show all posts
Showing posts with label penicillin. Show all posts
Tuesday, March 17, 2015
Classification of Penicillin with source and function
Classification of Penicillin
According to the source :
A) Natural penicillin
Oral: (1) Phenoxy-methyl-penicillin ( Penicillin- v), (2) Phenethicillin
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B) Semisynthetic penicillin (β-lactamase resistance)
1) Narrow spectrum penicillin ( penicillinase resistance ):
Oxacillin ,Cloxacillin, Flucloxacillin, Dicloxacillin, Nafcillin, Methicillin
2) Broad spectrum penicillin :
a) Penicillin which are active against both Gram (+ve) and Gram (-ve) bacteria and also effective apart from the organism (H. influenza, E.coli) sensitive to penicillin-G:
Ampicillin, Amoxacillin, Hetacillin.
b) Penicillin having borader actions than the above group :
Carbenicillin, Tricarcillin, Azlocillin
c) Newer penicillin :
Mezlocillin, Pivmecillin, Piperacillin .
According to the duration of action :
1) Short acting penicillin (4-6 hours) : most of the penicillin:
Ampicillin, Amoxacillin , Penicillin-V, Penicillin-G, Hetacillin, Carbenicillin, Tricarcillin , Azlocillin, Mezlocillin, Piperacillin.
2) Long acting penicillin :
Benzyl penicillin (7-30 days ), Benethamine penicillin (2-3 days), Procaine penicillin (12-24hours)
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